In the News

Oregon scientists get stem cells from cloned human embryos
2013-05-15 - Scientists at the Oregon Health and Science University accomplished in humans what has been done over the past 15 years in sheep, mice, cattle and several other species. The achievement is likely to, at least temporarily, reawaken worries about “reproductive cloning” — the production of one-parent duplicate humans.
Scientists Clone Human Embryos To Make Stem Cells
2013-05-15 - Scientists say they have, for the first time, cloned human embryos capable of producing embryonic stem cells.
Defects in Developmental Pathway Associated with Congenital Condition of Heart-Lung Connection
2013-05-12 - Jonathan A. Epstein, MD, Chair of the Department of Cell and Developmental Biology and Director of IRM Program in Regenerative Cardiovascular Biology at the Perelman School of Medicine, University of Pennsylvania, and colleagues from The Children’s Hospital of Philadelphia, describe in Nature Medicine, that a molecule called Semaphorin 3d (Sema3d) guides the development of endothelial cells and is crucial for normal development of pulmonary veins. They found that mutations in Sema3d cause embryonic blood vessels to hook up in the wrong way.
Tweaking Gene Expression to Repair Lungs
2013-02-25 - IRM Scientific Director and Professor of Cell and Developmental Biology, Ed Morrisey, PhD, is looking at how epigenetics controls lung repair and regeneration.   Using genetic and pharmacological approaches, they showed that development of progenitor cells in the lung is specifically regulated by the combined function of two highly related HDACs, HDAC/1 and /2.  Morrisey and colleagues published their findings in this week’s issue of Developmental Cell.
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  • May 29, 2013
    IRM Stem Cell Club
    Smilow Center for Translational Research 9-146 A/B